14. Jalan-Sakrikar, N.; Field, J. R.; Klar, R.; Mattman, M. E.; Walker, A. G.; Zamorano, R.; Xiang, Z.; Byers, C. F.; Blobaum, A. L.; Engers, D. W.; Weaver, C. D.; Days, E.; Utley, T. J.; Melancon, B. J.; Daniels, J. S.; Wood, M. R.; Lindsley, C. W.; Conn, P. J.; Hopkins, C. R.; Niswender, C. M.*, The discovery and characterization of a centrally penetrant (ML396) and a peripherally restricted (ML397) pan-Group III mGlu positive allosteric modulators, 2014, Bookshelf ID: pending.
13. Berry, C.; Locuson, C. W.; Daniels, J. S.; Lindsley, C. W.; Hopkins, C. R.*Discovery and characterization of ML398, a potent and selective chiral morpholine based antagonist of the dopamine (D4) receptor, 2014, Bookshelf ID: pending.
12. Engers, D. W.; Frist, A. Y.; Lindsley, C. W.; Hong, C. C.; Hopkins, C. R.*Development of a potent and ALK2 selective bone morphogenetic protein receptor (BMP) inhibitor, 2013, Bookshelf ID: pending.
11. Engers, D. W.; Bollinger, S. R.; Ennis, E. A.; Wright, J.; Wu, M.; Ruggiero, A. M.; McManus, O. B.; Lin, Z.; Huang, X.; Blakely, R. D.; Lindsley, C. W.; Li, M.; Hopkins, C. R.*Discovery and structure-activity relationship of a novel choline transporter inhibitor, 2013, Bookshelf ID: pending.
10. Engers, D. W.; Jones, C. K.; Bubser, M.; Thompson, A. D.; Blobaum, A. L.; Sheffler, D. J.; Zamorano, R.; Carrington, S. J. S.; Bridges, T. M.; Morrison, R. D.; Daniels, J. S.; Conn, P. J.; Lindsley, C. W.; Niswender, C. M.; Hopkins, C. R.*Discovery of a novel metabotropic glutamate receptor 4 (mGlu4) positive allosteric modulator (PAM) extended probe: characterization of ML292, a potent and selective mGlu4 PAM which produces efficacy alone or in combination with L-DOPA in preclinical rodent models of Parkinson’s disease, 2012, Bookshelf ID: NBK121452. PMID: 23658969.
9. Salovich, J. M.; Sheffler, D. J.; Vinson, P. N.; Lamsal, A.; Utley, T. J.; Blobaum, A. L.; Bridges, T. M.; Le, U.; Jones, C. K.; Wood, M. R.; Daniels, J. S.; Conn, P. J.; Engers, J.; Niswender, C. M.; Lindsley, C. W.; Hopkins, C. R.*Discovery of a novel structural class of M4 positive allosteric modulators: characterization of ML293, N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicotinamide, with CNS exposure in rats, 2012, Bookshelf ID: NBK143538. PMID: 23762944.
8. Yu, H.; Xu, K.; Huang, X.; Long, S.; Wu, M.; McManus, O. B.; Engers, J. L.; Mattmann, M. E.; Engers, D. W.; Lu, U. M.; Lindsley, C. W.; Hopkins, C. R.; Li, M. Identification of a novel, small molecule activator of KCNQ1 channels, 2011, Bookshelf ID: NBK143558. PMID: 23762928.
7. Niswender, C. M.; Rodriguez, A. L.; Sheffler, D. J.; Utley, T. J.; Vinson, P. N.; Dawson, E. S.; Jones, C. K.; Wood, M. R.; Daniels, J. S.; Conn, P. J.; Engers, J. L.; Le, U. M.; Melancon, B. J.; Hopkins, C. R.; Lindsley, C. W. Extended Probe Characterization: Development of an M4 PAM with Improved Activity and Brain Exposure, while Avoiding Species Bias, 2011, Bookshelf ID: NBK143536. PMID: 23762942.
6. Yu, H.; Xu, K.; Zou, B.; Wu, M.; McManus, O. B.; Engers, J. L.; Cheung, Y.-Y.; Salovich, J. M.; Hopkins, C. R.; Lindsley, C. W.; Li, M. Identification of a novel, small molecule inhibitor of KCNQ2 channels, 2011, Bookshelf ID: NKB121469. PMID: 23658963.
5. Yu, H.; Wu, M.; Hopkins, C. R.; Engers, J.; Townsend, S.; Lindsley, C.; McManus, O. B.; Li, M. A small molecule activator of KCNQ2 and KCNQ4 channels, 2011, Bookshelf ID: NBK121449. PMID: 23658954.
4. Miller, M. R.; Shi, J.; Wu, M.; Engers, J.; Hopkins, C. R.; Lindsley, C. W.; Salovich, J. M.; Zhu, Y.; Tian, J.-B.; Zhu, M. X.; McManus, O. B.; Li, M. Novel chemical inhibitor of TRPC4 Channels, 2011, Bookshelf ID: NBK61987. PMID: 22049577.
3. Hopkins, C. R.; Engers, D. W.; Niswender, C. M.; Jones, C. K.; Dawson, E.; Weaver, C. D.; Daniels, J. S.; Conn, P. J.; Lindsley, C. W. Discovery of a potent, selective and orally active in vivo mGlu4 positive allosteric modulator, 2010, Bookshelf ID: NBK143194. PMID: 23762961.
2. Wu, M.; Wang, H.-r.; Yu, H.; Makhina, E.; Xu, J.; Dawson, E. S.; Hopkins, C. R.; Lindsley, C. W.; McManus, O. B.; Li, M. A potent and selective small molecule Kir2.1 inhibitor. 2010, Bookshelf ID: NBK50692. PMID: 21433384.
1. Hopkins, C. R.; Niswender, C. M.; Lewis, L. M.; Weaver, C. D.; Lindsley, C. W. Discovery of a potent, selective and in vivo active mGluR4 positive allosteric modulator. 2010, Bookshelf ID: NBK50684. PMID: 21433377.