41. “Discovery and characterization of novel small molecules as in vivo tool compounds for addiction and bone disorders”, Invited talk at the University of Michigan, Department of Chemistry, Ann Arbor, MI, January 28th, 2020.
40. “Discovery and characterization of novel small molecules as in vivo tool compounds for CNS disorders”, Invited talk at the University Duquesne College of Pharmacy, Department of Pharmaceutical Sciences, Pittsburgh, PA, October 3rd, 2019.
39. “Discovery and characterization of novel small molecules as in vivo tool compounds for CNS disorders”, Invited talk at the University of Pittsburgh, Department of Chemistry, Pittsburgh, PA, October 2nd, 2019.
38. “Discovery and characterization of novel small molecules as in vivo tool compounds for CNS disorders”, Invited talk at the University of Texas Medical Branch at Galveston, Galveston, TX, January 25th, 2019.
37. “Novel MrgX1 Allosteric Agonists as Non-Habit Forming Anti-Chronic Pain Therapeutics”, Hopkins, C. R. Invited talk at the 5th Annual Symposium on Personalized Nano-Medicine. Talk given in the “Novel Approaches to Counteract the Current Opioid Epidemic” session, Miami, FL, November 1st, 2018.
36. “The synthesis, optimization and biological characterization of a novel series of D4 antagonists as potential novel targets for drug abuse”, Hopkins, C. R. Invited talk at the 2018 CPDD 80thAnnual Scientific Meeting. Talk given in the “Novel Targets for Drug Abuse Therapy” session, San Diego, CA, June 14th, 2018
35. “Discovery and optimization of novel, small molecules as in vivotool compounds and beyond”, Hopkins, C. R. Invited talk at the Omaha Veterans Affairs Hospital, Omaha, NE, April 18th, 2018.
34. "Discovery and optimization of novel, small molecules as in vivo tool compounds and beyond", Hopkins, C. R. Invited talk at the University of North Carolina Eschelman School of Pharmacy, Chapel Hill, NC, March 28th, 2018.
33. “Discovery and characterization of novel small molecules as in vivo tool compounds and beyond”, Hopkins, C. R. Invited talk at the University of Illinois at Chicago, Chicago, IL, Department of Chemistry, May 9th, 2017
32. “From mosquitocides to CNS disorders: the role of the medicinal chemist”, Hopkins, C. R. Invited talk at University of Nebraska – Omaha, Omaha, NE, Department of Chemistry, January 9th, 2017.
31. “From mosquitocides to neurodisease: the role of the medicinal chemist”, Hopkins, C. R. Invited talk at University of Nebraska – Lincoln, Lincoln, NE, Department of Chemistry, October 3rd, 2016.
30. “Positive allosteric modulators of mGlu4 for the treatment of Parkinson’s disease: From HTS to pre-clinical leads”, Hopkins, C. R. Invited talk presented in the GPCR-Based Drug Discovery: Signaling and Pharmacological Complexities session at the 14th Discovery on Target: Boston, MA, September 22nd, 2016.
29. “Discovery and optimization of novel, small molecules as in vivo tool compounds and beyond”, Hopkins, C. R. Invited talk at Purdue University, Department of Medicinal Chemistry and Molecular Pharmacology, West Lafayette, IN, March 10th, 2016.
28. “Discovery and Development of Small Molecules as Potential First-In-Class Therapeutics”, Hopkins, C. R. Invited talk at Indiana University-Purdue University Indianapolis, Department of Chemistry & Chemical Biology, Indianapolis, IN, January 27th, 2016.
27. “Discovery and optimization of novel, small molecules as in vivo tool compounds and beyond”, Hopkins, C. R. Invited talk at the University of Notre Dame, Department of Chemistry and Biochemistry and the Warren Center for Drug Discovery and Development, Notre Dame, IN, January 25th, 2016.
26. “Positive Allosteric Modulators of mGlu4 for the Treatment of Parkinson’s Disease: From HTS to Pre-clinical Leads”, Hopkins, C. R. Invited talk presented at Southern Research, Department of Drug Discovery, Birmingham, AL, January 15th, 2016.
25. “Discovery and optimization of novel, small molecules as in vivo tool compounds and beyond”, Hopkins, C. R. Invited talk at the University of Florida, College of Pharmacy, Gainesville, FL, January 11 – 12th, 2016.
24. “Ion channel therapeutics: a medicinal chemist’s perspective”, Hopkins, C. R. Invited talk presented at 2nd Annual Glom-NExT Symposium, Center for Glomerular Kidney Disease and Novel Experimental Therapeutics, Harvard Medical School, Boston, MA, October 19th, 2015.
23. “Allosteric Modulators of GPCRs – Practical Approaches”, Hopkins, C. R. Invited talk as part of Pre-Conference Short Course on Allosteric Modulators of GPCRs (PAMs, NAMs) at the 12th Annual Mastering Medicinal Chemistry, Boston, MA, June 9th, 2015.
22. “Discovery and Development of Small Molecules as Potential First-In-Class Therapeutics”, Hopkins, C. R. Invited talk at Michigan State University, Department of Pharmacology and Toxicology, East Lansing, MI, April 7 – 8th, 2015
21. “Positive Allosteric Modulators of mGlu4 for the Treatment of Parkinson’s Disease: From HTS to Pre-clinical Leads”, Hopkins, C. R. Invited talk presented at GPCR Drug Discovery – Identification and Optimization of Positive Allosteric Modulators for Difficult Targets, New York Academy of Sciences, New York, NY, March 24th, 2015.
20. “Discovery and Development of Small Molecules as Potential First-In-Class Therapeutics”, Hopkins, C. R. Invited talk at Purdue University, Department of Medicinal Chemistry and Molecular Pharmacology, West Lafayette, IN, February 10 – 11th, 2015.
19. “Discovery and Development of Small Molecule, In Vivo Active Compounds as Potential First-in-Class Therapeutics”, Hopkins, C. R. Invited talk at the National Institutes of Health, National Institute of Neurological Disorders and Stroke, Bethesda, MD, January 28th, 2015.
18. “Discovery and optimization of novel, small molecules as in vivo tool compounds and beyond”, Hopkins, C. R. Invited talk at the University of Wisconsin-Madison, School of Pharmacy, Madison, WI, January 8 – 9th, 2015.
17. “Chemical considerations for hit triage: From hit-to-lead”, Hopkins, C. R. Invited talk at Michigan State University, Drug Discovery Lecture Series, East Lansing, MI, October 31st, 2014.
16. “Multiple models for industrial-academic collaborations in CNS drug discovery”, Hopkins, C. R. (Lindsley, C. W.). Abstracts of Papers, Oral Presentation at the 248th National Meeting of the American Chemical Society: San Francisco, CA: Paper ID: 319. August 2014.
15. “Novel mGlu4 Positive Allosteric Modulators for the Treatment of Parkinson’s Disease”, Hopkins, C. R.* Invited talk presented in the GPCR-Targeted Therapeutics: Progressing Drug Candidates session at the 11th Discovery on Target: Boston, MA, September 25th, 2013.
14. “Preclinical validation of mGluR4 activation as a potentially groundbreaking treatment for Parkinson’s disease”, Hopkins, C. R.*, Invited talk presented in the Mining the Metabotropic Glutamate Receptors Type 4 (mGluR4) and Their Ligands in Brain Disorders session at the 25th European College of Neuropsychopharmacology: Vienna, Austria, October 16th, 2012, Session S.24.
13. “Vanderbilt Center for Neuroscience Drug Discovery: Translating Basic Science into Patient Care”, Hopkins, C. R., Keynote Address at the Regenerative Medicine in Gluacoma Symposium: Nashville, TN, Sept. 20th, 2012.
12. “Insights into the SAR of modulators of GPCRs and Ion Channels: From Allosteric Modulation to Mode Switching”, Hopkins, C. R., Invited talk at Givaudan Flavors Corp., Cincinnati, OH. September 4th, 2012.
11. “The Discovery and Development of Positive Allosteric Modulators of mGlu4 for the Treatment of Parkinson’s Disease”, Hopkins, C. R.*, Invited talk presented in the 2nd Annual Targeting Parkinson’s Disease Symposium at the 11th Annual World Pharma Congress: Drug Discovery Summit: Philadelphia, PA, June 4th, 2012.
10. “Discovery and optimization of novel, small molecule probes for central nervous disorders”, Hopkins, C. R.*Abstracts of Papers, Invited talk presented in Chemical Neuroscience session at the 243rd National Meeting of the American Chemical Society: San Diego, CA: Abstract 379, March 2012.
9. “Discovery and Development of Positive Allosteric Modulators of mGlu4 for the Treatment of Parkinson’s Disease”, Hopkins, C. R.*, Invited talk presented in the Targeting Parkinson’s Disease Symposium at the 10th Annual World Pharma Congress: Drug Discovery Summit: Philadelphia, PA, June 9th, 2011.
8. “Utilizing a Technology Enabled Synthetic Approach to Discovery Novel In Vivo Tool Compounds as Potential Therapeutics for Parkinson’s Disease”, Hopkins, C. R.*, Invited talk presented in the Technology Enabled Organic Synthesis Symposium at the 42nd Meeting of the American Chemical Society Central Region: Indianapolis, IN, June 8th, 2011.
7. “Drug Discovery in an Academic Setting – it is possible!”, Hopkins, C. R.*, Invited talk presented at the American Chemical Society Pharma Leaders Meeting: Abbott Laboratories, Abbott Park, IL, November 11–12, 2010.
6. “Discovery, Characterization, and Antiparkinsonian Effect of a Series of Heterobiarylamides as Positive Allosteric Modulators of Metabotropic Glutamate Receptor 4”, Hopkins, C. R.*, Invited talk presented at the 32nd National Medicinal Chemistry Symposium: Minneapolis, MN, June 2010.
5. “The Development of Positive Allosteric Modulators of mGluR4 for the Treatment of Parkinson’s Disease”, Hopkins, C. R. Invited talk presented the Vanderbilt Institute of Chemical Biology: Nashville, TN, March 2010.
4. “Allosteric Modulators: An Overview and the Discovery and SAR of Positive Allosteric Moculators of mGluR4 as a Potentially Novel Therapeutic Direction for the Treatment of Parkinson’s Disease”, Hopkins, C. R., Invited talk presented at the ACS Prospectives: Tactical Approaches to the Challenge of Drug Failure: Philadelphia, PA, October 2009.
3. “Vanderbilt Program in Drug Discovery: Drug and Ligand Discovery in Academia”, Hopkins, C. R., Invited talk presented at Center for Chemical Genomics Symposium, Screening and Beyond: Assays, hits, probes, leads…drugs: University of Michigan, Ann Arbor, MI, May 2009.
2. “Discovery and SAR of Positive Allosteric Modulators of mGluR4 as a Potentially Novel Therapeutic Direction for the Treatment of Parkinson’s Disease”, Hopkins, C. R., Abstracts of Papers, Invited talk presented in the Latest Developments in Glutamate Receptors session at the 237th National Meeting of the American Chemical Society: Salt Lake City, UT: Abstract 139, March 2009.
1. “Discovery and SAR of Positive Allosteric Modulators of mGluR4 as a Potentially Novel Therapeutic Direction for the Treatment of Parkinson’s Disease”, Hopkins, C. R. Invited talk presented at Molecular Medicine Tri-Conference, Mastering Medicinal Chemistry, San Francisco, CA, February 2009.